Protein identification by mass spectrometry (MS) or MS/MS
Description: Identification of proteins in biological samples, either by intact protein analysis (MALDI-TOF) or protein digestion followed by peptide mass fingerprinting (PMF, MS) or peptide fragmentation (MS/MS).
Applications: Protein analysis, characterization of biological samples, analysis of protein interactions (e.g. pull-down assays).
Determination of molecular mass of peptides, proteins and other biomolecules.
Description: Analysis of intact proteins, peptides and other biomolecules such as oligonucleotides using mass spectrometry (MALDI-TOF or ESI-Q-TOF) for the determination of their exact molecular mass.
Applications: Characterization of biomolecules.
Sample preparation for proteomic analysis
Description: This service includes all necessary steps to prepare samples for different proteomic analyses: protein extraction from tissues, cells or fluids, precipitation, cleaning, desalting, quantification and digestion (in gel or in solution) with proteolytic enzimes (trypsin, chymotrypsin, lys-C…), to obtain the correspondent peptides.
Applications: All experiments involving proteins.
Description:
The service includes the housing of mice or rats to be able to carry out longitudinal studies, the administration, if applicable, of contrast agents, or radiopharmaceuticals for PET. Acquisition of both T1-weighted and T2-weighted images, as well as colocalized with the PET image. Volume measurement.
Applications:
In addition to the typical studies in 3T preclinical imaging equipment, the possibility of varying the angle of the bed with respect to the horizontal makes it especially interesting for vascular and plant studies.
Modification of oligonucleotides during and post synthesis to meet user requirements:
