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U28-S04. High Resolution Liquid NMR (Onsite&Remote) OUTSTANDING

Liquid NMR is a fundamental tool both in chemistry and biomedicine research. Its applications to chemistry range from structure elucidation of small molecules to studies of ligand-protein interactions. In biomedicine, the use of liquid NMR has expanded from the classical metabolic studies using enriched stable isotope tracers to the more recent NMR-based metabolomics of biofluids (urine, plasma, CSF).

Applications:
>> Structure verification and elucidation
>> Molecular mobility: determination of conformation in solution
>> Determination of enantiomeric excess
>> Kinetic and temperature studies of reaction mixtures
>> Metabolomics of liquid samples (CSF, plasma, urine and tissue extracts)
>> Metabolomics of liquid samples (CSF, plasma, urine and tissue extracts)

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U28-S03. Computed Tomography (CT) (Onsite&Remote)

Computerised Tomography (CT) allows high quality 3D imaging of preclinical animal models based on the reconstruction of 2D X-ray images captured at different angles. Albira uses dedicated beds for rats and mice with incorporated gas anesthesia. Different image capture modes allow users to balance capture time and image quality. The Albira software suite automates the reconstruction process, while the included PMOD software allows users to perform advance analyses and to export data into popular formats such as DICOM. It allows the possibility of combining CT data with fluorescence.

Applications:
>> Tumour imaging and quantification
>> Bone and implantation studies
>> Anatomical CT data is often used in conjunction with other modalities including fluorescence

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U28-S02. Fluorescent and Bioluminescent Optical Imaging (Onsite&Remote) OUTSTANDING

The use of fluorescent and bioluminescent techniques for small animal-based studies into cancer, arthritis and heart disease have grown tremendously in recent years. Part of the Multimodal Imaging Service, Bionand offers the Carestream In-Vivo Xtreme animal imaging system which allows up to five mice to visualized simultaneously using fluorescence and bioluminence methods.

Applications:
>> Tumour and Stem Cell Tracking
>> Monitoring of Drug Delivery and Targeting
>> High throughput Pharmacodynamic studies
>> Imaging and validating new Probes and Biomarkers
>> Bionand offers a range of complimentary services including animal housing facilities, and histology, microscopy and cytometry services

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U28-S01. Magnetic Resonance Imaging (MRI) (Onsite&Remote) OUTSTANDING

Magnetic Resonance Imaging (MRI) is a very versatile technique that offers not only excellent morphological information, but also functional and physiological. Furthermore, important advances during last years in the development of highly sensitive contrast agents using nanotechnology approaches have brought MRI into the molecular imaging arena. Thus, small animal MRI scanners have become a key tool in the development of magnetic nanoparticles for medical diagnosis and therapy.

Applications:
>> Anatomical Studies: tumors, inflammation, Degenerative diseases, etc.
>> Functional Studies: brain perfusion, vascular permeability, in vivo metabolic profiling, etc.
>> Pharmocokinetics and Biodistribution of new Contrast Agents (or any drug magnetically labeled)
>> Monitoring of Drug Delivery and Targeting
>> Follow up of Therapy Response

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U26-S05. Training Advice and assistance (On-site&Remote)

Training Advice and assistance (On-site&Remote)

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U10-S09. Characterization and development of pulmonar formulations (On-site&Remote) OUTSTANDING

Characterization and development of pulmonar formulations

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U10-S08. 3D bio-impression of scaffolding for regenerative medicine (On-site&Remote) OUTSTANDING

3D bio-impression of scaffolding for regenerative medicine

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U23-S09. Quality control for Human Assisted Reproduction clinics (On-site&Remote) OUTSTANDING

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U23-S08. Oosight system (On-site&Remote) OUTSTANDING

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U23-S07. Laser System and Biopsed of blastomeres (On-site&Remote) OUTSTANDING

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