The technique HPLC-DAD-(SPE) -NMR/MS is suitable for the analysis of mixtures. Combining high-resolution liquid chromatography with detection techniques NMR spectroscopy, mass spectrometry (MS) and diode array detection (DAD). (http://sct.uab.cat/sermn/en/content/complex-mixtures)
Non-invasive manner to record high-resolution MRI images, and do spectroscopy focused on biological samples, small animals or plants, and other materials (http://sct.uab.cat/sermn/en/content/magnetic-resonance-imaging-mri)
Hyperpolarization of samples allows to work with highly polarized nuclear spins in solution, afording a considerable sensitivity gain (http://sct.uab.cat/sermn/en/content/dnp-0)
Use of the equipment for the fixation of living tissue
Access to specific software and database. Software packages include, among others, the INTERPRET decision-support system for human brain tumour diagnosis based on MRS and SpectraClassifier, for pattern recognition of in vivo MRS data single and multivoxel are developed and distributed through the platform (http://gabrmn.uab.es).
Minimally invasive surgery images (laparoscopy, endoscopy, microsurgery, interventionalradiology); ultrasonographyimages; CAT images; MRI; fluoroscopyimages.
Micromanipulation and microinjection oocyte; IMSI system; Embryo biopsy systems (Saturn Laser); vision systems of the mitotic spindle (Oosight system)
Embryo selection; collection and transport for the study in animal models
Biopsed of blastomeres; oocyte microinjection; Oocyte and embryo cryopreservation; Implantation Studies
Preclinical efficacy assays in
Preclinical evaluation of efficacy according to European Directives; In vivo models for the pilot feasibility; Biocompatibility. Animal models of human diseases: diabetes, obesity, hypercholesterolemia, hypertriglyceridemia, acute and chronic myocardial infarction, prostatic hyperplasia, ulcers, pleural adhesions, constrictive pericarditis, and abdominal aortic aneurysm among other; Animal species: rodents, rabbits, dogs, cats, pigs and sheep. Creation of different pathologies: oncological, cardiovascular, ophthalmology, transplants, assisted reproduction, cell therapy, etc.
Efficacy and safety of medical devices and biomaterials. Efficacy and toxicity studies of new molecules and pharmaceutical forms.
Murine model embryo tranfers; intracytoplasmic microinjection, oocyte vitrification, measurement and analysis of samples of Natural Killer cells (NK), seminogram and semen studies.
